BDBM683258 4-(5-(3-amino-8-azabicyclo [3.2.1]octan-8-carbonyl)- 2-(1-(cyanomethyl)-5- fluoro-1H-indazol-6- yl)thiophen-3-yl)-2-fluoro- benzonitrile::US20240216357, Example 215

SMILES NC1CC2CCC(C1)N2C(=O)c1cc(c(s1)-c1cc2n(CC#N)ncc2cc1F)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=XEEFKYRIDLSNAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 683258   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683258(US20240216357, Example 215 | 4-(5-(3-amino-8-azabi...)
Affinity DataIC50: 0.450nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683258(US20240216357, Example 215 | 4-(5-(3-amino-8-azabi...)
Affinity DataIC50: 1.14E+4nMAssay Description:A manual patch-clamp technology is used to evaluate whether the test compound has a potential inhibitory effect on a voltage-gated potassium ion chan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
Go to US Patent