BDBM683184 4-(5-(4- aminopiperidin- 1-yl)-8- (4-fluoro-3- hydroxyphenyl) imidazolo[1,2-c] pyrimidin-7-yl]-2- fluorobenzonitrile::US20240216357, Example 137

SMILES NC1CCN(CC1)c1nc(-c2ccc(C#N)c(F)c2)c(-c2ccc(F)c(O)c2)c2nccn12

InChI Key InChIKey=BNNAODVJPJIPNE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 683184   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683184(US20240216357, Example 137 | 4-(5-(4- aminopiperid...)
Affinity DataIC50: 0.0700nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683184(US20240216357, Example 137 | 4-(5-(4- aminopiperid...)
Affinity DataIC50: 1.00E+4nMAssay Description:A manual patch-clamp technology is used to evaluate whether the test compound has a potential inhibitory effect on a voltage-gated potassium ion chan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
Go to US Patent