BDBM683171 4-(5-(4- aminopiperidin-1- yl)-8-3-hydroxy-4- (methoxyphenyl) imidazolo[1,2-c] pyrimidin-7- yl)-2- fluorobenzonitrile::US20240216357, Example 124

SMILES COc1ccc(cc1O)-c1c(nc(N2CCC(N)CC2)n2ccnc12)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=HCSAQIRIRKRLLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 683171   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683171(US20240216357, Example 124 | 4-(5-(4- aminopiperid...)
Affinity DataIC50: 0.0800nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683171(US20240216357, Example 124 | 4-(5-(4- aminopiperid...)
Affinity DataIC50: 3.00E+4nMAssay Description:A manual patch-clamp technology is used to evaluate whether the test compound has a potential inhibitory effect on a voltage-gated potassium ion chan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
Go to US Patent