BDBM683147 4-(6-(4-aminopiperidin-1- yl)-3-(3-hydroxy-4- methylphenyl)-4- methoxypyridin-2-yl)-2- fluorobenzonitrile hydrochloride::US20240216357, Example 95

SMILES COc1cc(nc(-c2ccc(C#N)c(F)c2)c1-c1ccc(C)c(O)c1)N1CCC(N)CC1

InChI Key InChIKey=TULPBDKVNCSKDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 683147   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683147(US20240216357, Example 95 | 4-(6-(4-aminopiperidin...)
Affinity DataIC50: 0.160nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683147(US20240216357, Example 95 | 4-(6-(4-aminopiperidin...)
Affinity DataIC50: 6.92E+3nMAssay Description:A manual patch-clamp technology is used to evaluate whether the test compound has a potential inhibitory effect on a voltage-gated potassium ion chan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
Go to US Patent