BDBM683065 Preparation of 4-(5-(3-amino-8-azabicyclo[3.2.1]octane-8-carbonyl)-2-(5-fluoro-3-pentylbenzo[d]isoxazol-6-yl) thiophen-3-yl)-2-fluorobenzonitrile formate::US20240216357, Example 9

SMILES Cc1noc2cc3c4sc(cc4c4cc(F)c(cc4c3cc12)C#N)C(=O)N1C2CCC1CC(N)C2

InChI Key InChIKey=GGWBYXXCEQMKLH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 683065   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683065(US20240216357, Example 9 | Preparation of 4-(5-(3-...)
Affinity DataIC50: 0.0260nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683065(US20240216357, Example 9 | Preparation of 4-(5-(3-...)
Affinity DataIC50: 2.10E+3nMAssay Description:A manual patch-clamp technology is used to evaluate whether the test compound has a potential inhibitory effect on a voltage-gated potassium ion chan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
Go to US Patent