BDBM669548 US20240132473, Compound I-21

SMILES COc1cc2nn(CCS(=N)(=O)c3ccncc3)cc2cc1NC(=O)c1cnn2cccnc12

InChI Key InChIKey=DGXUHBZBNBSUJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 669548   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Shanghai Xunhe Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM669548(US20240132473, Compound I-21)
Affinity DataIC50: 0.5nMAssay Description:The inhibitory activity (IC50) of the compound on IRAK4 kinase under Km ATP was detected by mobility shift assay (MSA). Ten drug concentration gradie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
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