BDBM661263 4-((3-(1-cyclopropyl-1H- 1,2,4-triazol-3-yl)-5-fluoro-2- methoxy phenyl)amino)-6- ((2,6-dimethyl pyridin-4-yl)- amino)-N-ethyl nicotinamide::US20240101548, Compound 204

SMILES CCONC(=O)c1cnc(Nc2cc(C)nc(C)n2)cc1Nc1cc(F)cc(-c2ncn(n2)C2CC2)c1OC

InChI Key InChIKey=QMEBADDSYLUAGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661263   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Shenzhen Chipscreen Biosciences Co.

US Patent
LigandPNGBDBM661263(4-((3-(1-cyclopropyl-1H- 1,2,4-triazol-3-yl)-5-flu...)
Affinity DataIC50: 0.0600nMAssay Description:Compound of the present invention formulated into different concentrations (series 3 times dilutions, started from 60 μM, 11 concentrations in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent