BDBM6574 (6-Methoxy-1H-2-indolyl)(1H-2-indolyl)methanone::2-(1H-indol-2-ylcarbonyl)-6-methoxy-1H-indole::Bis(1H-2-indolyl)methanone 12::CHEMBL7602

SMILES COc1ccc2cc([nH]c2c1)C(=O)c1cc2ccccc2[nH]1

InChI Key InChIKey=RSMLCEQJLGXMPQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 6574   

TargetPlatelet-derived growth factor receptor beta(Human)
University of Regensburg

LigandPNGBDBM6574(2-(1H-indol-2-ylcarbonyl)-6-methoxy-1H-indole | CH...)
Affinity DataIC50: 300nMpH: 7.4 T: 2°CAssay Description:The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM6574(2-(1H-indol-2-ylcarbonyl)-6-methoxy-1H-indole | CH...)
Affinity DataIC50: 300nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM6574(2-(1H-indol-2-ylcarbonyl)-6-methoxy-1H-indole | CH...)
Affinity DataIC50: 890nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed