BDBM651841 US20240051955, Compound Formula II::US20240051955, Compound Formula III

SMILES Nc1nccc2n([C@@H]3CCCN(C3)C(=O)C(O)CO)c(=O)n(-c3ccc(Oc4ccccc4)cc3)c12

InChI Key InChIKey=YFCOQAPINNCEGI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 651841   

TargetTyrosine-protein kinase BTK(Human)
Genzyme

US Patent
LigandPNGBDBM651841(US20240051955, Compound Formula III | US2024005195...)
Affinity DataIC50: 279nMAssay Description:Compounds of Formula Ib, Formula II, and Formula III were tested against BTK(h) as described herein. All compounds tested were prepared to a working ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Genzyme

US Patent
LigandPNGBDBM651841(US20240051955, Compound Formula III | US2024005195...)
Affinity DataIC50: 1.38E+3nMAssay Description:Compounds of Formula Ib, Formula II, and Formula III were tested against BTK(h) as described herein. All compounds tested were prepared to a working ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent