BDBM645008 (S)-6-((1-(2-Fluoro-5-((6-methylpyridin-3-yl)oxy)phenyl)ethyl)amino)-3-isopropyl-1,3,5-triazine-2,4(1H,3H)-dione 12::US20240010639, Example 12

SMILES CC(C)n1c(=O)nc(N[C@@H](C)c2cc(Oc3ccc(C)nc3)ccc2F)[nH]c1=O

InChI Key InChIKey=LQAONLQADPKHAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645008   

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM645008(US20240010639, Example 12 | (S)-6-((1-(2-Fluoro-5-...)
Affinity DataIC50: 810nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent