BDBM645002 (S)-6-((1-(5-Cyclopropyl-2-fluorophenyl)ethyl)amino)-3-isopropyl-1,3,5-triazine-2,4(1H,3H)-dione 6::US20240010639, Example 6

SMILES CC(C)n1c(=O)nc(N[C@@H](C)c2cc(ccc2F)C2CC2)[nH]c1=O

InChI Key InChIKey=GZZLCTQNPNQHOQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645002   

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM645002(US20240010639, Example 6 | (S)-6-((1-(5-Cyclopropy...)
Affinity DataIC50: 450nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent