BDBM631418 US20230348421, Compound 61

SMILES CN1CCC(CC1)N(Cc1ncc(F)cc1F)C(=O)NCc1ccc2OC(C)(C)Cc2c1

InChI Key InChIKey=NGOJDYOEOHSCOE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 631418   

Target5-hydroxytryptamine receptor 2A(Human)
Geneora Pharma (Shijiazhuang) Co.

US Patent
LigandPNGBDBM631418(US20230348421, Compound 61)
Affinity DataIC50: 3.32nMAssay Description:CHO-K1/5-HT2A cells in the logarithmic growth phase were seeded into a 384-well plate at a density of 10000 cells per well, and cultured in a 37° C.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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Target5-hydroxytryptamine receptor 2A(Human)
Geneora Pharma (Shijiazhuang) Co.

US Patent
LigandPNGBDBM631418(US20230348421, Compound 61)
Affinity DataIC50: 31.2nMAssay Description:NIH3T3-5HT2AR cells in the logarithmic growth phase were seeded into a white-wall clear-bottom 96-well plate at a density of 1000 cells per well, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Geneora Pharma (Shijiazhuang) Co.

US Patent
LigandPNGBDBM631418(US20230348421, Compound 61)
Affinity DataIC50: 2.55E+3nMAssay Description:CHO (Chinese Hamster Ovary) cells stably expressing hERG potassium channels were taken, and hERG potassium channel currents were recorded at room tem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent