BDBM631402 US20230348421, Compound 31
SMILES CN1CCC(CC1)N(Cc1ccc(F)cc1)C(=O)NCc1ccc2OC(C)(C)Cc2c1
InChI Key InChIKey=ZVMBOTDFKQXEDW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 631402
Affinity DataIC50: 17.4nMAssay Description:CHO-K1/5-HT2A cells in the logarithmic growth phase were seeded into a 384-well plate at a density of 10000 cells per well, and cultured in a 37° C.,...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:NIH3T3-5HT2AR cells in the logarithmic growth phase were seeded into a white-wall clear-bottom 96-well plate at a density of 1000 cells per well, and...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Geneora Pharma (Shijiazhuang) Co.
US Patent
Geneora Pharma (Shijiazhuang) Co.
US Patent
Affinity DataIC50: 1.85E+3nMAssay Description:CHO (Chinese Hamster Ovary) cells stably expressing hERG potassium channels were taken, and hERG potassium channel currents were recorded at room tem...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at human prefrontal cortex 5-HT2A receptor assessed as increase in [35S]GTPgammaS binding by liquid scintillation spectromet...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inverse agonist activity at human 5-HT2A receptor expressed in cell membrane assessed as increase in [35S]GTPgammaS binding by liquid scintillation s...More data for this Ligand-Target Pair
Affinity DataKi: 0.00300nMAssay Description:Displacement of [3H]ketanserin human recombinant 5-HT2A receptor by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Displacement of [3H]ketanserin from human brain cortex 5-HT2A receptor by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair