BDBM620430 US11767305, Compound (+)-BK-5-MAPB::US20250019357, Compound (+)-BK-5MAPB

SMILES CN[C@@H](C)C(=O)c1ccc2occc2c1

InChI Key InChIKey=GKZGRACLZFHCFE-UHFFFAOYSA-N

Data  1 KI  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 620430   

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620430(US11767305, Compound (+)-BK-5-MAPB | US20250019357...)
Affinity DataIC50: 2.09E+3nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
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Target5-hydroxytryptamine receptor 1B(Rat)
Tactogen

US Patent
LigandPNGBDBM620430(US11767305, Compound (+)-BK-5-MAPB | US20250019357...)
Affinity DataEC50:  3.07E+3nMAssay Description:The 5-HT1BR cAMP secondary messenger agonist assay used a panel of CHO-K1 cell lines stably expressing non-tagged GPCRs that endogenously signal thro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620430(US11767305, Compound (+)-BK-5-MAPB | US20250019357...)
Affinity DataIC50: 3.80E+4nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620430(US11767305, Compound (+)-BK-5-MAPB | US20250019357...)
Affinity DataIC50: 2.09E+3nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620430(US11767305, Compound (+)-BK-5-MAPB | US20250019357...)
Affinity DataEC50:  439nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620430(US11767305, Compound (+)-BK-5-MAPB | US20250019357...)
Affinity DataKi:  1.70E+4nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent