| Assay Method Information | |
| | 5-HT1BR cAMP Secondary Messenger Agonist Assay |
| Description: | The 5-HT1BR cAMP secondary messenger agonist assay used a panel of CHO-K1 cell lines stably expressing non-tagged GPCRs that endogenously signal through cAMP. Hit Hunter® cAMP assays monitored the activation of a GPCR via Gi and Gs secondary messenger signaling in a homogenous, non-imaging assay format using DiscoverX Enzyme Fragment Complementation (EFC) with β-galactosidase as the functional endpoint. |
| Affinity data for this assay | |
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