BDBM608709 US11697650, Compound 35::US11697650, Example 18

SMILES Oc1ccc(cc1)N(Cc1c(Cl)ccc(F)c1F)C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12

InChI Key InChIKey=RRVIMHXVZZKFSY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 608709   

TargetApoptosis regulator Bcl-2(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM608709(US11697650, Compound 35 | US11697650, Example 18)
Affinity DataIC50: 30nMAssay Description:The following assay concentrations and times were used: 3 ng BCL-2, 5 μl of 1:100 anti-His Tb-labeled donor, 5 μl of 1:100 Dye-labeled acce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
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TargetBcl-2-like protein 1(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM608709(US11697650, Compound 35 | US11697650, Example 18)
Affinity DataIC50: 4.00E+3nMAssay Description:The following assay concentrations and times were used: 10.5 ng BCL-XL, 5 μl of 1:100 anti-His Tb-labeled donor, 5 μl of 1:100 Dye-labeled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
Go to US Patent

LigandPNGBDBM608709(US11697650, Compound 35 | US11697650, Example 18)
Affinity DataIC50: 4.00E+3nMAssay Description:The following assay concentrations and times were used: 10 ng MCL-1, 5 μl of 1:200 anti-His Tb-labeled donor, 5 μl of 1:200 Dye-labeled acc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
Go to US Patent