BDBM594033 (S)-5-(5-(7-amino-7-(hydroxymethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)-2-isopropoxybenzonitrile::US11584726, Example 3

SMILES CC(C)Oc1ccc(cc1C#N)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1

InChI Key InChIKey=UMHXCYAPYLEZHQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594033   

TargetSphingosine 1-phosphate receptor 5(Human)
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594033(US11584726, Example 3 | (S)-5-(5-(7-amino-7-(hydro...)
Affinity DataEC50:  250nMAssay Description:The sample to be tested was dissolved in DMSO and diluted with detection buffer solution in 3-fold dilution. A reagent and a positive control were di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594033(US11584726, Example 3 | (S)-5-(5-(7-amino-7-(hydro...)
Affinity DataIC50: 7.80E+3nMAssay Description:HEK293 engineering cells stably expressed with hERG potassium channel were used to test the compounds. Patch Clamp Detection: The cells were separate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent