BDBM594032 (S)-(2-amino-7-(5-(3,4-diethoxyphenyl)-1,3,4-oxadiazol-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl)methanol::US11584726, Example 13

SMILES CCOc1ccc(cc1OCC)-c1nnc(o1)-c1ccc2CC[C@@](N)(CO)Cc2c1

InChI Key InChIKey=FQRLKHMVWRAWRE-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594032   

TargetSphingosine 1-phosphate receptor 5(Human)
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594032(US11584726, Example 13 | (S)-(2-amino-7-(5-(3,4-di...)
Affinity DataEC50: >1.00E+4nMAssay Description:The sample to be tested was dissolved in DMSO and diluted with detection buffer solution in 3-fold dilution. A reagent and a positive control were di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594032(US11584726, Example 13 | (S)-(2-amino-7-(5-(3,4-di...)
Affinity DataIC50: 1.20E+3nMAssay Description:HEK293 engineering cells stably expressed with hERG potassium channel were used to test the compounds. Patch Clamp Detection: The cells were separate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent