BDBM588055 US11541023, Compound 3

SMILES NCc1ccc(NC(=O)c2cc3ccccc3cc2O)cc1

InChI Key InChIKey=VRZLGSXKZZLNLO-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 588055   

TargetKallikrein-6(Human)
Sarbonne Universite

US Patent
LigandPNGBDBM588055(US11541023, Compound 3)
Affinity DataIC50: 1.17E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
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TargetKallikrein-6(Human)
Sarbonne Universite

US Patent
LigandPNGBDBM588055(US11541023, Compound 3)
Affinity DataIC50: 2.38E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (MBP3) and 1 μl o...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
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TargetKallikrein-6(Human)
Sarbonne Universite

US Patent
LigandPNGBDBM588055(US11541023, Compound 3)
Affinity DataIC50: 1.23E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (PAR2) and 1 μl o...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
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TargetKallikrein-1(Human)
Sarbonne Universite

US Patent
LigandPNGBDBM588055(US11541023, Compound 3)
Affinity DataIC50: 5.90E+3nMAssay Description:Table 4: The molecules were tested in order to evaluate their possible inhibitory effect on the enzymatic activity of KLK1. The % inhibitions were de...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
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TargetPlasminogen(Human)
Sarbonne Universite

US Patent
LigandPNGBDBM588055(US11541023, Compound 3)
Affinity DataIC50: 3.75E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetPlasminogen(Human)
Sarbonne Universite

US Patent
LigandPNGBDBM588055(US11541023, Compound 3)
Affinity DataIC50: 3.25E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (PAR4) and 1 μl o...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetKallikrein-6(Human)
Sarbonne Universite

US Patent
LigandPNGBDBM588055(US11541023, Compound 3)
Affinity DataKi:  790nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetPlasminogen(Human)
Sarbonne Universite

US Patent
LigandPNGBDBM588055(US11541023, Compound 3)
Affinity DataKi:  1.32E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent