BDBM581421 US11505532, Compound WX091::US12077513, Compound of formula (IV)

SMILES CC(C)n1nc(nc1C1CC1)-c1ccc(OC\C(CN)=C\F)cc1

InChI Key InChIKey=ANEXDGJMMZCGNQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 581421   

TargetAmine oxidase [copper-containing] 3(Human)
Shandong Danhong Pharmaceutical

US Patent
LigandPNGBDBM581421(US11505532, Compound WX091 | US12077513, Compound ...)
Affinity DataIC50: 1.20nMAssay Description:The inhibition of the sample on VAP-1 enzyme activity was measured by using an Amplex Red Monoamine Oxidase kit (Invitrogen #A12214). 100 nL of the g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 2(Human)
Shandong Danhong Pharmaceutical Co.

US Patent
LigandPNGBDBM581421(US11505532, Compound WX091 | US12077513, Compound ...)
Affinity DataIC50: 1.20nMAssay Description:Amplex Red Monoamine Oxidase Kit (Invitrogen #A12214) was used to determine the inhibitory effects of the sample on VAP-1 enzyme activity. 100 nL Tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 2(Human)
Shandong Danhong Pharmaceutical Co.

US Patent
LigandPNGBDBM581421(US11505532, Compound WX091 | US12077513, Compound ...)
Affinity DataIC50: 0.710nMAssay Description:Amplex Red Monoamine Oxidase Kit (Invitrogen #A12214) was used to determine the inhibitory effects of the sample on VAP-1 enzyme activity. 100 nL Tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
Go to US Patent