BDBM578212 US11478474, Compound 57::US12070457, Compound 57

SMILES C[C@H]1CN(CCN1c1ccc(Nc2cc(cn(C)c2=O)-c2ccnc(c2CO)-n2ccn3c4ccccc4c(F)c3c2=O)nc1)C1COC1

InChI Key InChIKey=SMOCDJOBNFXWNR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 578212   

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578212(US11478474, Compound 57 | US12070457, Compound 57)
Affinity DataIC50: 6nMAssay Description:Z′-LYTE biochemical assay employs a fluorescence resonance energy transfer (FRET)based, coupled-enzyme format and is based on the differential ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578212(US11478474, Compound 57 | US12070457, Compound 57)
Affinity DataIC50: 6nMAssay Description:The experiment were carried out according to the instructions of the Z′-LYTE kinase test kit-tyrosine 1 peptide. Reagent preparation: 1.33�� ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2024
Entry Details
Go to US Patent