BDBM578189 US11478474, Compound 34::US12070457, Compound 34

SMILES Cn1cc(cc(Nc2ccc(cn2)N2CCN(CC2=O)C2COC2)c1=O)-c1ccnc(c1CO)-n1ccn2c3CC(C)(C)Cc3cc2c1=O

InChI Key InChIKey=KAOQOQSDABPODE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 578189   

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578189(US11478474, Compound 34 | US12070457, Compound 34)
Affinity DataIC50: 5nMAssay Description:Z′-LYTE biochemical assay employs a fluorescence resonance energy transfer (FRET)based, coupled-enzyme format and is based on the differential ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578189(US11478474, Compound 34 | US12070457, Compound 34)
Affinity DataIC50: 5nMAssay Description:The experiment were carried out according to the instructions of the Z′-LYTE kinase test kit-tyrosine 1 peptide. Reagent preparation: 1.33�� ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2024
Entry Details
Go to US Patent