BDBM578174 US11478474, Compound 100::US11478474, Compound 101::US11478474, Compound 19::US11478474, Compound 223::US11478474, Compound 38::US11478474, Compound 39::US11478474, Compound 94::US11478474, Compound 97::US12070457, Compound 101

SMILES C[C@H]1CN(CCN1c1ccc(Nc2cc(cn(C)c2=O)-c2ccnc(c2CO)-n2ccn3c4CC(C)(C)Cc4cc3c2=O)nc1)C1COC1

InChI Key InChIKey=AHCYLQZSJZNAJF-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 578174   

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 8nMAssay Description:Z′-LYTE biochemical assay employs a fluorescence resonance energy transfer (FRET)based, coupled-enzyme format and is based on the differential ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 1nMAssay Description:Z′-LYTE biochemical assay employs a fluorescence resonance energy transfer (FRET)based, coupled-enzyme format and is based on the differential ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 24nMAssay Description:Z′-LYTE biochemical assay employs a fluorescence resonance energy transfer (FRET)based, coupled-enzyme format and is based on the differential ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 7nMAssay Description:Z′-LYTE biochemical assay employs a fluorescence resonance energy transfer (FRET)based, coupled-enzyme format and is based on the differential ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 9nMAssay Description:Z′-LYTE biochemical assay employs a fluorescence resonance energy transfer (FRET)based, coupled-enzyme format and is based on the differential ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 5nMAssay Description:Z′-LYTE biochemical assay employs a fluorescence resonance energy transfer (FRET)based, coupled-enzyme format and is based on the differential ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 6nMAssay Description:Z′-LYTE biochemical assay employs a fluorescence resonance energy transfer (FRET)based, coupled-enzyme format and is based on the differential ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 3.00E+3nMAssay Description:Z′-LYTE biochemical assay employs a fluorescence resonance energy transfer (FRET)based, coupled-enzyme format and is based on the differential ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 8nMAssay Description:The experiment were carried out according to the instructions of the Z′-LYTE kinase test kit-tyrosine 1 peptide. Reagent preparation: 1.33�� ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 1nMAssay Description:The experiment were carried out according to the instructions of the Z′-LYTE kinase test kit-tyrosine 1 peptide. Reagent preparation: 1.33�� ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 24nMAssay Description:The experiment were carried out according to the instructions of the Z′-LYTE kinase test kit-tyrosine 1 peptide. Reagent preparation: 1.33�� ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 7nMAssay Description:The experiment were carried out according to the instructions of the Z′-LYTE kinase test kit-tyrosine 1 peptide. Reagent preparation: 1.33�� ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 9nMAssay Description:The experiment were carried out according to the instructions of the Z′-LYTE kinase test kit-tyrosine 1 peptide. Reagent preparation: 1.33�� ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 5nMAssay Description:The experiment were carried out according to the instructions of the Z′-LYTE kinase test kit-tyrosine 1 peptide. Reagent preparation: 1.33�� ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578174(US11478474, Compound 19 | US11478474, Compound 38 ...)
Affinity DataIC50: 6nMAssay Description:The experiment were carried out according to the instructions of the Z′-LYTE kinase test kit-tyrosine 1 peptide. Reagent preparation: 1.33�� ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2024
Entry Details
Go to US Patent