BDBM576175 WO2022056448, Compound 46

SMILES C[C@H]([C@@H]1c2ccc(OCC\C=C\Cc3ccc(cc3)C(=O)N3CCc4ccc1cc4C3)nc2)C(O)=O

InChI Key InChIKey=GJLAVSDHBUDAFE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576175   

TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Human)
Sanofi

WIPO

LigandBDBM576175(WO2022056448, Compound 46)Copy SMILESCopy InChI

Affinity DataIC50: 0.350nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/14/2022
Entry Details
Copy Entry DOIWIPO WO2022056448

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