BDBM519522 US11142505, FAH-74

SMILES CN1C(N)=NC(C1=O)(c1ccc(OC(F)F)cc1)c1cccc(c1)-c1cncnc1

InChI Key InChIKey=ANTDWUJSWGGYRX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519522   

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandPNGBDBM519522(US11142505, FAH-74)
Affinity DataIC50: 10nMAssay Description:Approximately 200 nM to 10 μM substrate, approximately 10 to 200 pM enzyme, and approximately 0.1 nM to 10 μM of the agent(s), in aqueous s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
Go to US Patent