BDBM512915 US11091444, Compound FAH-5::US11142505, FAH-05

SMILES CN1C(N)=NC(C1=O)(c1cc(C)cc(C)c1)c1cc(F)cc(F)c1

InChI Key InChIKey=OLKWRTZAQAQQMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 512915   

TargetAmyloid-beta precursor protein(Human)
Buck Institute For Research On Aging

US Patent
LigandPNGBDBM512915(US11142505, FAH-05 | US11091444, Compound FAH-5)
Affinity DataIC50: 5.00E+3nMAssay Description:β-sectretase inhibitor IV from Calbiochem (cat #565788).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
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TargetBeta-secretase 1(Human)
University of California

US Patent
LigandPNGBDBM512915(US11142505, FAH-05 | US11091444, Compound FAH-5)
Affinity DataIC50: 6.46E+3nMAssay Description:Approximately 200 nM to 10 μM substrate, approximately 10 to 200 pM enzyme, and approximately 0.1 nM to 10 μM of the agent(s), in aqueous s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
Go to US Patent