BDBM512557 US11091444, Compound FAH-1::US11142505, FAH-01

SMILES CN1C(N)=NC(C1=O)(c1ccccc1)c1cc(F)cc(F)c1

InChI Key InChIKey=YCOJVPUXRDIMND-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 512557   

TargetAmyloid-beta precursor protein(Human)
Buck Institute For Research On Aging

US Patent
LigandPNGBDBM512557(US11142505, FAH-01 | US11091444, Compound FAH-1)
Affinity DataIC50: 3.00E+3nMAssay Description:β-sectretase inhibitor IV from Calbiochem (cat #565788).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
Go to US Patent

TargetAmyloid-beta precursor protein(Human)
Buck Institute For Research On Aging

US Patent
LigandPNGBDBM512557(US11142505, FAH-01 | US11091444, Compound FAH-1)
Affinity DataKd:  5.00E+3nMAssay Description:β-sectretase inhibitor IV from Calbiochem (cat #565788).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandPNGBDBM512557(US11142505, FAH-01 | US11091444, Compound FAH-1)
Affinity DataIC50: 2.67E+3nMAssay Description:Approximately 200 nM to 10 μM substrate, approximately 10 to 200 pM enzyme, and approximately 0.1 nM to 10 μM of the agent(s), in aqueous s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
Go to US Patent