BDBM50630187 CHEMBL5413402::US12247029, Entry 95

SMILES Oc1ccc(CCn2c(SCC(=O)Nc3nccs3)nc3nccnc3c2=O)cc1

InChI Key InChIKey=MHDLQWIWWOGXGG-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630187   

TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Leibniz-Fmp

Curated by ChEMBL

LigandBDBM50630187(CHEMBL5413402 | US12247029, Entry 95)Copy SMILESCopy InChI

Affinity DataIC50: 210nMAssay Description:Inhibition of PI3KC2alpha deltaN domain (unknown origin) preincubated for 5 mins followed by substrate addition and measured after 20 mins in the pre...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/20/2024
Entry Details
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Leibniz-Fmp

Curated by ChEMBL

LigandBDBM50630187(CHEMBL5413402 | US12247029, Entry 95)Copy SMILESCopy InChI

Affinity DataIC50: 210nMAssay Description:ADP-Glo kinase assay was performed as described by the manufacturer's protocol. Briefly, the kinase assay was performed with a 5 mixture of liver...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/15/2025
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL