BDBM50630186 CHEMBL5401086::US12247029, Entry 44

SMILES O=C(CSc1nc2nccnc2c(=O)n1CCC1CCCCC1)Nc1nccs1

InChI Key InChIKey=QROLBQOBNAFCLM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630186   

TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Leibniz-Fmp

Curated by ChEMBL

LigandBDBM50630186(CHEMBL5401086 | US12247029, Entry 44)Copy SMILESCopy InChI

Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of PI3KC2alpha deltaN domain (unknown origin) preincubated for 5 mins followed by substrate addition and measured after 20 mins in the pre...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/20/2024
Entry Details
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Leibniz-Fmp

Curated by ChEMBL

LigandBDBM50630186(CHEMBL5401086 | US12247029, Entry 44)Copy SMILESCopy InChI

Affinity DataIC50: 590nMAssay Description:ADP-Glo kinase assay was performed as described by the manufacturer's protocol. Briefly, the kinase assay was performed with a 5 mixture of liver...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/15/2025
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL