BDBM50630159 CHEMBL5402925::US12247029, Entry 22

SMILES O=C(CSc1nc2nccnc2c(=O)n1CCc1ccccc1)Nc1ccccc1

InChI Key InChIKey=QDCZHRQYLSTDNY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50630159   

LigandPNGBDBM50630159(CHEMBL5402925 | US12247029, Entry 22)
Affinity DataIC50: 500nMAssay Description:Inhibition of PI3KC2alpha deltaN domain (unknown origin) preincubated for 5 mins followed by substrate addition and measured after 20 mins in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandPNGBDBM50630159(CHEMBL5402925 | US12247029, Entry 22)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of PI3KC2beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandPNGBDBM50630159(CHEMBL5402925 | US12247029, Entry 22)
Affinity DataIC50: 3.30E+3nMAssay Description:ADP-Glo kinase assay was performed as described by the manufacturer's protocol. Briefly, the kinase assay was performed with a 5 mixture of liver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2025
Entry Details
Go to US Patent