BDBM50625296 CHEMBL5437856

SMILES Cc1cc2-c3cc(CS(C)(=O)=O)ccc3N(Cc3c[nH]c(=O)c1n23)C(=O)c1ccc2ccccc2c1

InChI Key InChIKey=GZEDEKFDZMUCGJ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50625296   

TargetBromodomain-containing protein 4(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625296(CHEMBL5437856)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human N-terminal 6His-tagged BRD4 BD2 (351 to 457 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells using biotinylated...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625296(CHEMBL5437856)
Affinity DataIC50: 57nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625296(CHEMBL5437856)
Affinity DataIC50: 44nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625296(CHEMBL5437856)
Affinity DataIC50: 79nMAssay Description:Inhibition of BRD2 BD1 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625296(CHEMBL5437856)
Affinity DataIC50: 28nMAssay Description:Inhibition of BRD2 BD2 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625296(CHEMBL5437856)
Affinity DataIC50: 46nMAssay Description:Inhibition of BRD3 BD1 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625296(CHEMBL5437856)
Affinity DataIC50: 19nMAssay Description:Inhibition of BRD3 BD2 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain testis-specific protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625296(CHEMBL5437856)
Affinity DataIC50: 87nMAssay Description:Inhibition of BRDT BD1 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain testis-specific protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625296(CHEMBL5437856)
Affinity DataIC50: 43nMAssay Description:Inhibition of BRDT BD2 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed