BDBM50625295 CHEMBL5440806

SMILES Cc1cc2-c3cc(CS(C)(=O)=O)ccc3N(Cc3c[nH]c(=O)c1n23)C(=O)c1cccc2ccccc12

InChI Key InChIKey=SVWVGWHDUPYUFQ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50625295   

TargetBromodomain-containing protein 4(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625295(CHEMBL5440806)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human N-terminal 6His-tagged BRD4 BD2 (351 to 457 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells using biotinylated...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625295(CHEMBL5440806)
Affinity DataIC50: 415nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625295(CHEMBL5440806)
Affinity DataIC50: 106nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625295(CHEMBL5440806)
Affinity DataIC50: 471nMAssay Description:Inhibition of BRD2 BD1 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625295(CHEMBL5440806)
Affinity DataIC50: 111nMAssay Description:Inhibition of BRD2 BD2 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625295(CHEMBL5440806)
Affinity DataIC50: 261nMAssay Description:Inhibition of BRD3 BD1 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625295(CHEMBL5440806)
Affinity DataIC50: 50nMAssay Description:Inhibition of BRD3 BD2 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain testis-specific protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625295(CHEMBL5440806)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of BRDT BD1 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain testis-specific protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50625295(CHEMBL5440806)
Affinity DataIC50: 59nMAssay Description:Inhibition of BRDT BD2 (unknown origin) using biotinylated H4 peptide as substrate preincubated for 15 mins followed by SA-Tb and GST-XL665 addition ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed