BDBM50555734 CHEMBL4746603

SMILES COc1ccccc1CNC(=O)C(\C)=C\CC\C(C)=C\CC\C(C)=C\CC[C@]1(C)CCc2cc(O)cc(C)c2O1

InChI Key InChIKey=QUKQYPVUJLLDQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50555734   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Univ Angers

Curated by ChEMBL
LigandPNGBDBM50555734(CHEMBL4746603)
Affinity DataIC50: 76nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21(DE3) assessed as reduction in LTB4 and 5-H(P)ETE formation using arachidonic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Univ Angers

Curated by ChEMBL
LigandPNGBDBM50555734(CHEMBL4746603)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-LO in human PMNL cells assessed as reduction in LTB4, 5-H(P)ETE, 12-HETE and 15-HETE products formation using arachidonic acid as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed