| Assay Method Information | |
| | ChEMBL_2053474 (CHEMBL4708475) |
| Description: | Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21(DE3) assessed as reduction in LTB4 and 5-H(P)ETE formation using arachidonic acid as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured after 10 mins by RP-HPLC method |
| Affinity data for this assay | |
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