BDBM50519880 CHEMBL4518713

SMILES Cc1onc(c1C(=O)Nc1ccc(cc1)C(O)=O)-c1c(Cl)cccc1C(F)(F)F

InChI Key InChIKey=YEPQOFBDMBVDLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519880   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Technische Universiteit Eindhoven

Curated by ChEMBL
LigandPNGBDBM50519880(CHEMBL4518713)
Affinity DataIC50: 5.00E+4nMAssay Description:Inverse agonist activity at His6-tagged PPARgamma LBD (unknown origin) assessed as inhibition of rosiglitazone-induced N-terminal biotinylated co-act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Technische Universiteit Eindhoven

Curated by ChEMBL
LigandPNGBDBM50519880(CHEMBL4518713)
Affinity DataIC50: 1.00E+5nMAssay Description:Inverse agonist activity at human N-terminal His6-tagged RORgammat LBD (265 to 518 residues) expressed in Escherichia coli BL21 (DE3) assessed as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed