BDBM50516013 CHEMBL4583516

SMILES COc1cc(N2CC(C2)NC(=O)c2ccc3nnc(C)c(C)c3c2)c(Cl)cn1

InChI Key InChIKey=PIAJWVKYPWXIEB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516013   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50516013(CHEMBL4583516)
Affinity DataEC50:  373nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50516013(CHEMBL4583516)
Affinity DataEC50:  356nMAssay Description:Positive allosteric modulation of rat M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed