| Assay Method Information | |
| | ChEMBL_1863035 (CHEMBL4363891) |
| Description: | Positive allosteric modulation of human M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium mobilization incubated with EC20 ACh for 140 secs and subsequent EC80 Ach addition further incubated for 120 secs by Fluo-4-AM dye based fluorescence assay |
| Affinity data for this assay | |
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