BDBM50511789 CHEMBL4474132

SMILES CC(C)(C)c1ccc(cc1)-c1cc(CNCC2CCNCC2)sc1-c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=WEJUPZWNBLRNHH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50511789   

TargetHistone acetyltransferase KAT2B(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511789(CHEMBL4474132)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged PCAF expressed in Escherichia coli BL21 codon plus cells using Histone H3 peptide (1 to 21) and [3H]acetyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT6A [507-778](Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511789(CHEMBL4474132)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged Myst3 expressed in Escherichia coli BL21 codon plus cells using Histone H3 peptide (1 to 21) and [3H]acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511789(CHEMBL4474132)
Affinity DataIC50: 620nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511789(CHEMBL4474132)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of His6-tagged p300 HAT domain (unknown origin) assessed as disruption of p300 and Histone H4 (1-21) peptide interaction incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511789(CHEMBL4474132)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human GST-tagged CBP HAT domain expressed in Escherichia coli BL21 codon plus cells using Histone H3 peptide (1 to 21) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed