BDBM50491106 CHEMBL2377105

SMILES Nc1nc(nc2sc(Cc3ccccc3)cc12)-c1cccc(n1)C#N

InChI Key InChIKey=BCIJZIDPONGWKE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50491106   

TargetAdenosine receptor A2a(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50491106(CHEMBL2377105)
Affinity DataKi:  26nMAssay Description:Antagonist activity at human adenosine A2a receptor expressed in CHOK1 cells assessed as inhibition of NECA/forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50491106(CHEMBL2377105)
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in CHOK1 cells assessed as inhibition of R-PIA/forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed