BDBM50441019 CHEMBL304786

SMILES Clc1ccc(\C=C2/OC(=O)c3ccccc23)cc1

InChI Key InChIKey=OHRFHJYUEWVXBD-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50441019   

TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50441019(CHEMBL304786)
Affinity DataIC50: 4.81E+4nMAssay Description:Antagonist activity at rat recombinant TRPM8 overexpressed in HEK293 cells assessed as inhibition of menthol-induced intracellular calcium influx pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50441019(CHEMBL304786)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at rat recombinant TRPA1 overexpressed in HEK293 cells assessed as induction of intracellular calcium influx by Fluo-4-AM dye-based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50441019(CHEMBL304786)
Affinity DataIC50: 1.49E+4nMAssay Description:Antagonist activity at rat recombinant TRPM8 overexpressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium influx prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50441019(CHEMBL304786)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at rat recombinant TRPA1 overexpressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced intracellular calci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed