BDBM50308028 4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine::CHEMBL596802::US20230414596, Compound Pridopidine::US20240261273, Compound Pridopidine

SMILES CCCN1CCC(CC1)c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=YGKUEOZJFIXDGI-UHFFFAOYSA-N

Data  16 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50308028   

TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  17nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  57nMAssay Description:In-vitro binding assays performed at Eurofins Panlabs Taiwan, Ltd. Specific ligand binding was determined in the presence of an excess of unlabelled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  57nMAssay Description:In-vitro binding assays performed at Eurofins Panlabs Taiwan, Ltd. Specific ligand binding was determined in the presence of an excess of unlabelled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  57nMAssay Description:In vitro binding assay performed at Eurofins Panlabs Taiwan, ltd. Specific ligand binding was determined in the presence of an excess of unlabelled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2024
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  82nMAssay Description:Inhibition of [3H](+)-pentazocine binding to human sigma1 receptor expressed in HEK293 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  82nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  82nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi: >1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  5.45E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2024
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  5.45E+3nMAssay Description:In-vitro binding assays performed at Eurofins Panlabs Taiwan, Ltd. Specific ligand binding was determined in the presence of an excess of unlabelled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  5.45E+3nMAssay Description:In vitro binding assay performed at Eurofins Panlabs Taiwan, ltd. Specific ligand binding was determined in the presence of an excess of unlabelled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2024
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  7.50E+3nMAssay Description:Binding affinity to dopamine D2 (high) receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  7.52E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity to D2R receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  1.75E+4nMAssay Description:Binding affinity to dopamine D2 (low) receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  1.76E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed