BDBM50235042 CHEMBL4068032

SMILES COc1ccc(N2CCOCC2)c2sc(NC(=O)C(C)(C)Oc3ccc(F)cc3)nc12

InChI Key InChIKey=NIIBSIMWHVDFED-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50235042   

TargetAdenosine receptor A2a(Human)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235042(CHEMBL4068032)
Affinity DataKi:  4.20nMAssay Description:Antagonist activity at human adenosine A2A receptor expressed in HEK293 cell membranes assessed as decrease in CGS-21680/forskolin-induced cAMP level...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235042(CHEMBL4068032)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cell membranes measured after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235042(CHEMBL4068032)
Affinity DataKi:  13nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in HEK293 cells measured by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A1(Human)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235042(CHEMBL4068032)
Affinity DataKi:  2.00E+3nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cell membranes assessed as decrease in CPA/forskolin-induced cAMP level pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235042(CHEMBL4068032)
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes measured after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235042(CHEMBL4068032)
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of [3H]-HEMADO from human adenosine A3 receptor expressed in HEK293 cell membranes measured after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235042(CHEMBL4068032)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]-MRS-1754 from human adenosine A2B receptor expressed in HEK293 cell membranes measured after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed