BDBM50086871 CHEMBL3426388

SMILES COc1ccc(cc1)-n1nnc(n1)-c1ccccc1NC(=O)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=QONKIYDRXVUBPV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50086871   

LigandPNGBDBM50086871(CHEMBL3426388)
Affinity DataIC50: 118nMAssay Description:Inhibition of GFP-tagged human BCRP expressed in MDCK2 cells pre-incubated for 30 mins followed by Hoechst 33342 addition and further incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2016
Entry Details Article
PubMed
LigandPNGBDBM50086871(CHEMBL3426388)
Affinity DataIC50: 535nMAssay Description:Inhibition of ABCG2 in human H460/MX20 cells assessed as potentiation of mitoxantrone induced antiproliferative activity by measuring mitoxantrone IC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50086871(CHEMBL3426388)
Affinity DataIC50: 587nMAssay Description:Inhibition of ABCG2 in human H460/MX20 cells assessed as potentiation of mitoxantrone induced antiproliferative activity by measuring mitoxantrone IC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50086871(CHEMBL3426388)
Affinity DataIC50: 378nMAssay Description:Inhibition of ABCG2 in human H460/MX20 cells assessed as potentiation of mitoxantrone induced antiproliferative activity by measuring mitoxantrone IC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed