| Assay Method Information | |
| | ChEMBL_1696306 (CHEMBL4047196) |
| Description: | Inhibition of ABCG2 in human H460/MX20 cells assessed as potentiation of mitoxantrone induced antiproliferative activity by measuring mitoxantrone IC50 at 1 uM preincubated for 2 hrs followed by mitoxantrone addition measured after 72 hrs by MTT assay (Rvb = 6.161 +/- 0.172 microM) |
| Affinity data for this assay | |
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