BDBM4869 3-(4-Chloroanilino)-4,5-dimethyl-6-(4-pyridylmethyl)-pyridazine::CGP79787 Analog 54::CHEMBL306707::N-(4-chlorophenyl)-4,5-dimethyl-6-(pyridin-4-ylmethyl)pyridazin-3-amine

SMILES Cc1c(C)c(Nc2ccc(Cl)cc2)nnc1Cc1ccncc1

InChI Key InChIKey=ISZLWQNNDFZBEE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4869   

TargetVascular endothelial growth factor receptor 1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM4869(N-(4-chlorophenyl)-4,5-dimethyl-6-(pyridin-4-ylmet...)
Affinity DataIC50: 260nMpH: 7.5 T: 2°CAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM4869(N-(4-chlorophenyl)-4,5-dimethyl-6-(pyridin-4-ylmet...)
Affinity DataIC50: 870nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM4869(N-(4-chlorophenyl)-4,5-dimethyl-6-(pyridin-4-ylmet...)
Affinity DataIC50: 870nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed