BDBM3887 (4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-2-({[benzyl(methyl)carbamoyl](propyl)amino}carbamoyl)-4-(benzyloxy)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamoyl}-2-methylbutyl]carbamoyl}-4-[(3S)-3-acetamido-3-formamidopropanoic acid]butanoic acid::Azapeptide-based compound 28

SMILES CCCN(NC(=O)[C@@H]1C[C@H](CN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)[C@@H](C)CC)C(C)C)OCc1ccccc1)C(=O)N(C)Cc1ccccc1

InChI Key InChIKey=WZCOUGAHCBBTHX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3887   

TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepacivirus C)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3887((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-2-({[benzyl(meth...)
Affinity DataIC50: 8.40E+3nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2005
Entry Details Article
PubMed