BDBM35881 5,6-di-p-tolyl-pyrazine-2-carboxylic acid phenylamide::5,6-diaryl-pyrazine-2-amide derivative, 7b::CHEMBL225242::N-phenyl-5,6-dip-tolylpyrazine-2-carboxamide

SMILES Cc1ccc(cc1)-c1ncc(nc1-c1ccc(C)cc1)C(=O)Nc1ccccc1

InChI Key InChIKey=AKCXCZPEESTMSV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35881   

TargetCannabinoid receptor 1(Human)
Astrazeneca

LigandPNGBDBM35881(N-phenyl-5,6-dip-tolylpyrazine-2-carboxamide | 5,6...)
Affinity DataIC50: 326nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Astrazeneca

LigandPNGBDBM35881(N-phenyl-5,6-dip-tolylpyrazine-2-carboxamide | 5,6...)
Affinity DataKi:  509nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed