BDBM340037 1-(2-chloro-3,6-difluorophenyl)-3-(3-fluoro- 4-(7-(5-methyl-1H-imidazol-2-yl)-1- oxoisoindolin-4-yl)phenyl)urea::US10604508, Compound 18::US11230539, Compound 18::US9758508, Compound 18

SMILES Cc1cnc([nH]1)-c1ccc(c2CNC(=O)c12)-c1ccc(NC(=O)Nc2c(F)ccc(F)c2Cl)cc1F

InChI Key InChIKey=MEJZNNSYMLXPFU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 340037   

TargetTyrosine-protein kinase BTK(Human)
Crystalgenomics

US Patent
LigandPNGBDBM340037(US9758508, Compound 18 | 1-(2-chloro-3,6-difluorop...)
Affinity DataIC50: 0.0700nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Crystalgenomics

US Patent
LigandPNGBDBM340037(US9758508, Compound 18 | 1-(2-chloro-3,6-difluorop...)
Affinity DataIC50: 0.0700nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Crystalgenomics

US Patent
LigandPNGBDBM340037(US9758508, Compound 18 | 1-(2-chloro-3,6-difluorop...)
Affinity DataIC50: 0.0700nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
Go to US Patent