BDBM25200 3-({6-methanesulfonyl-7-[2-(morpholin-4-ylmethyl)-1,3-thiazol-4-yl]quinolin-4-yl}amino)-4-methylphenol::4-Anilino-6,7-disubstituted quinoline, 40

SMILES Cc1ccc(O)cc1Nc1ccnc2cc(-c3csc(CN4CCOCC4)n3)c(cc12)S(C)(=O)=O

InChI Key InChIKey=KNLRJRUFOIDTER-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25200   

LigandPNGBDBM25200(3-({6-methanesulfonyl-7-[2-(morpholin-4-ylmethyl)-...)
Affinity DataIC50: 34nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compound was determined by incubation with Ret kinase and the substrate in the presence of ATP/ [gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed