BDBM22543 2-[4-(1H-imidazol-4-ylmethyl)phenyl]-4,4-dimethyl-4,5-dihydro-1,3-oxazole::4-Benzyl-1H-imidazole derivative, 11

SMILES CC1(C)COC(=N1)c1ccc(Cc2cnc[nH]2)cc1

InChI Key InChIKey=NSUJUQRJDQTZEV-UHFFFAOYSA-N

Data  1 KI  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22543   

TargetHistamine H4 receptor(Human)
Vu University Amsterdam

LigandPNGBDBM22543(2-[4-(1H-imidazol-4-ylmethyl)phenyl]-4,4-dimethyl-...)
Affinity DatapH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH4R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vu University Amsterdam

LigandPNGBDBM22543(2-[4-(1H-imidazol-4-ylmethyl)phenyl]-4,4-dimethyl-...)
Affinity DataKi:  2.51E+3nM ΔG°:  -7.63kcal/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed